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論文リスト

    2021年
  1. M. Tamai, Y. Fujiyama, and *Y. Tagawa, "Hepatocytes and endothelial networks in a fluid-based in vitro model of liver drug metabolism." Tissue Engineering part A Doi: 10.1089/ten.TEA.2020.0226, 2021
    2. 2020年
  2. E. Shimbo; S. Nukuzuma, and *Y. Tagawa. "Human iPS cell–derived astrocytes support efficient replication of progressive multifocal leukoencephalopathy-type JC polyomavirus." Biochem. Biophys. Res. Commun. 533:983-987. Doi: 10.1016/j.bbrc.2020.09.117. 2020
  3. K. Moriya, M. Tamai, T. Koga, T. Tanaka, and *Y. Tagawa. "Acetaminophen-induced hepatotoxicity of cultured hepatocytes depends on timing of isolation from light-cycle controlled mice. " Genes to Cells 25(4): 257-269. Doi:10.1111/gtc.12755, 2020
  4. Zhen Qi, Misato Kamoshida, Miho Tamai, Masamichi Hirose, and *Yoh-ichi Tagawa, "Mouse embryonic stem cell-derived cardiomyocytes with time dependent pharmacokinetics for drug screeing. " Translational and Regulatory Sciences 2: 7-13, doi.org/10.33611/trs.2_7, 2020
    5. 2019年
  5. M. Tamai, H. Uchisawa, Y. Saito, H. Matsue, M. Kawase, T. Naraoka, and *Y. Tagawa. "Acorbine, a Corbicula japonica-derived tripeptide containing non-proteinogenic amino acids, suppresses ethanol-induced liver injury. " Biochem. Biophys. Res. Commun. 522(3):580-584. Doi:10.1016/j.bbrc.2019.11.131., 2019
    6. 　　　　　　
  6. K. Akiyama, K. Fujisawa, H. Kondo, Y. Netsu, K. Nishikawa, Y. Takata, Y. Nakamura, Y. Kino, S. Ayukawa, M. Yamamura, N. Hayashi, Y. Tagawa, and N. Nakashima. "MazF activation causes ACA sequence-independent and selective alterations in RNA levels in Escherichia coli. " Arch. Micicrobiol. 2019 doi:10.1007/s00203-019-01726-9.
  7. H. Okumura, A. Nakanishi, S. Toyama, M. Yamanoue, K. Yamada, A. Ukai, T. Hashita, T. Iwao, T. Miyamoto, Y. Tagawa, M. Hirabayashi, I. Miyoshi, T. Matsunaga. "Contribution of rat embryonic stem cells to xenogeneic chimeras in blastocyst or 8-cell embryo injection and aggregation" Xenotransplantation, 2019   e12468, doi: 10.1111/xen.12468.
    8. 2018年
  8. T. Imada, K. Moriya, M. Uchiyama, M. Hitotsuyanagi, A. Masuda, S. Ayukawa, Y. Tagawa, N. Dohmae, M. Yamamura, D. Kiga.  "A highly bioactive Lys-deficient IFN leads to a site-specific di-PEGylated IFN with equivalent bioactivity to that of unmodified IFN-α2b" ACS Synthetic Biology, 7:2537-2546, 2018 doi: 10.1021/acssynbio.8b00188.
  9. R. Takata, T. Akasaka, M. Tamai, Y. Yoshimura, T. Taira, H. Miyaji, Y. Tagawa, S. Yamagata, J. Iida, Y. Yoshida. “Effect of a nano-scale fine hole pattern on the differentiation of RAW264.7 cells into osteoclasts” Digest Journal of Nanomaterials and Biostructures 13:451 – 458, 2018
  10. K. Muta, S. Inomata, T. adao, F. ukuhara, J. Nomura, T. Nishiyama, Y. Tagawa, S. Amano. “Inhibitory Effect of the Extract of Rhizome of Curcuma longa L in GelatinaseActivity and its Effect on Human Skin.” J. Biosci. Bioeng. 125:353-358, 2018, doi:10.1016/j.jbiosc.2017.10.001.   
    11. 2017年
  11. Ito M, Sun S, Fukuhara T, Suzuki R, Tamai M, Yamauchi T, Nakashima K, Tagawa YI, Okazaki S, Matsuura Y, Wakita T, *Suzuki T.　“Development of hepatoma-derived, bidirectional oval-like cells as a model to study host interactions with hepatitis C virus during differentiation.” Oncotarget 2017 doi: 10.18632/oncotarget.19108.
  12. Yu Toyoda, Kasumi Kashikura, Tomoyoshi Soga, *Yoh-ichi Tagawa, “Metabolomics of an in vitro liver model containing primary hepatocytes assembling around an endothelial cell network: comparative study on the metabolic stability and the effect of acetaminophen treatment” Journal of Toxicological Sciences in press.
  13. Yue, Y., M. Tamai, and *Y. Tagawa, “Nitric Oxide is Critical for Avoiding Hepatic Lipid Overloading via IL-6 Induction during Liver Regeneration after Partial Hepatectomy in Mice” Experimental Animals in press.  doi: 10.1538/expanim.17-0017.
  14. K. Nakajima, M. So, K. Takahashi,Y. Tagawa, M. Hirao, Y. Goto, and *H. Ogi : Optimized Ultrasonic Irradiation Finds Out Ultra-stable Aβ1－40 Oligomer, J. Phys. Chem. B 121:2603-2613, 2017. doi: 10.1021/acs.jpcb.7b01409
    15. 2016年
  15. *Furuzono, S., M. Meguro, S. Miyauchi, S. Inoue, T. Homma, K. Yamada, Y. Tagawa, F. Nara, and T. Nagayama: A novel aldosterone synthase inhibitor ameliorates mortality in pressure-overload mice with heart failure. European Journal of Pharmacology, 795:58-65, 2016. doi:10.1016/j.ejphar.2016.11.049
  16. Yagi, S., Y. Tagawa, and *N. Shiojiri: Transdifferentiation of mouse visceral yolk sac cells into parietal yolk sac cells in vitro. Biochem. Biophys. Res. Commun. 470(4):917-923, 2016, doi: 10.1016/j.bbrc.2016.01.149 .
    17. 2014年
  17. Ahn, S., M. Tamai, K. Nakashima, M. Ito, T. Suzuki, and *Y. Tagawa: An in vitro liver model consisting of endothelial vascular networks surrounded by human hepatoma cell lines allows for improved hepatitis B virus replication. J. Biosci. Bioeng. 118:107-111, 2014.
  18. Aratsu, F., I. Harada, S. Yoshimura, C.-S. Cho, T. Akaike, and Y. Tagawa: Dynamic chemotactic response of fibroblasts to local stimulation using EGF-immobilized microbeads. Biomaterials 35:2471-2476, 2014
  19. Aikawa, H., M. Tamai, K. Mitamura, F. Itmainati, G. N. Barber, and *Y. Tagawa: Innate immunity in an in vitro murine blastocyst model using embryonic and trophoblast stem cells. J. Biosci. Bioeng.117:358-365, 2014
  20. Shang, Y., M. Tamai, R. Ishii, N. Nagaoka, Y. Yoshida, M. Ogasawara, J. Yang, and *Y. Tagawa: Hybrid sponge comprised of galactosylated chitosan and hyaluronic acid mediates the co-culture of hepatocytes and endothelial cells.  J. Biosci. Bioeng. 117:99-106, 2014
    21. 2013年
  21. Miyanokoshi, M., T. Tanaka, M. Tamai, Y. Tagawa, and K. Wakasugi: Expression of the rodent-specific alternative splice variant of tryptophanyl-tRNA synthetase in murine tissues and cells. Sci.Rep. 3:3477. doi:1038/srep03477, 2013
  22. Tamai, M., M. Aoki, A. Nishimura, K. Morishita, and *Y. Tagawa: In vitro recapitulation of the urea cycle using murine embryonic stem cell-derived in vitro liver model. Amino Acids 45:1343-51, 2013
  23. Tamai, M., E. Adachi, and *Y. Tagawa: Characterization of a liver organoid tissue composed of hepatocytes and fibroblast in dense collagen fibrils.  Tissue Engineering part A  19:2527-2535, 2013
  24. Ryu, J.-Y., A. Siswanto, K. Harimoto, and *Y. Tagawa: Chimeric analysis of EGFP and DsRed2 transgenic mice demonstrates polyclonal maintenance of pancreatic acini. Transgenic Res. 22:549-556, 2013
    25. 2012年
  25. Harimoto, K., Y. Yoshida, K. Yoshihara, N. Nagaoka, T. Matsumoto, and * Y. Tagawa: Osteoblast compatibility of materials depends on serum protein absorbability in osteogenesis. Dental Materials Journal 31:674-680, 2012
  26. Haque, A., X.-S. Yue, A. Motazedian, Y. Tagawa, T. Akaike: Characterization and neural differentiation of mouse embryonic and induced pluripotent stem cells on cadherin-base substrata. Biomaterials 33:5094-5106, 2012
  27. Toyoda, Y., M. Tamai, K. Kashikura, S. Kobayashi, Y. Fujiyama, T. Soga, and *Y. Tagawa: Acetoaminophen-induced hepatotoxicity in a liver tissue model consisting of primary hepatocytes assembling around an endothelial cell network. Drug Metab. Dispos. 40:169-177, 2012
    28. 2011年
  28. Hayashi, T, A. Horiuchi, K. Sano, N. Hiraoka, M. Kasai, T. Ichimura, T. Sudo, Y. Tagawa, R. Nishimura, Ol Ishiko, Y. Kanai, N. Yaegashi, H. Aburatani, T. Shiozawa, I. Konishi : Potential role of LMP2 as tumor-suppressor defines new targets for uterine leiomyosarcoma therapy. Sci Rep, 1:180, 2011
  29. Tamai, M., A, Yamashita, and *Y. Tagawa: Mitochondrial development of the in vitro hepatic organogenesis model with simultaneous cardiac mesoderm differentiation from murine induced pluripotent stem cells.  J. Biosci. Bioeng. 112:495-500,2011
  30. Denda, K., K. Nkano-Wakabayashi, N. Okamoto, N. Kitamura, J. Ryu, Y. Tagawa, T. Ichisaka, S. Yamanaka, and M. Komada: Nrk, an X-linked protein kinase in the germinal center kinase family, is required for placental development and fetoplacental induction of labor.  J. Biol. Chem. 286:28802-28810, 2011
  31. Hikosaka, K., H. Noritake, W. Kimura, N. Sultana, M. T. K. Sharkar, Y. Tagawa, T. Uezato, Y. Kobayashi, T. Wakita, and N. Miura: Expression of human factors CD81, claudin-1, scavenger receptor, and occluding in mouse hepatocytes does not confer susceptibility to HCV entry.  Biomedical Research 32:143-150, 2011
    32. 2010年
  32. Sakai, H., *Y. Tagawa, M. Tamai, H. Motoyama, S. Ogawa, J. Soeda, T. Nakata, S. Miyagawa: Isolation and characterization of portal branch ligation-stimulated Hmga2-positive bipontent hepatic progenitor cells. Biochem. Biophys. Res. Commun. 403:298-304. 2010
  33. Hossain, S., A. Stanislaus, MJ, Chua, S. Tada, Y. Tagawa, EH. Chowdhury, T. Akaike: Carbonate apatite-facilitated intracellulary delivered siRNA for efficient knockdown of functional genes. J. Control. Release 147:101-108, 2010
  34. Higuchi, A., M. Tamai, Y. Tagawa, Y. Chang, and Q.-D. Ling: Surface modification of polymeric membranes for low protein binding. Membrane Water Treatment 1: 103-120, 2010
  35. Kyuwa, S., S. Takagaki, S. Matsuyama, F. Taguchi, J. Saegusa, Y. Iwakura, Y. Tagawa, and Y. Yoshikawa: Characterization of a variant virus from ascites of subacute granulomatous serositis in interferon-g-deficient C57BL/6 mice persistently infected with murine coronavirus, strain JHM.  Viral Immunology, 23:437-442, 2010
  36. Higuchi, A., S. Yang, P. Li, M. Tamai, Y. Tagawa, Y. Chang, Y. Chang, Q. Ling, and S. Hsu: Direct ex vivo expansion of hematopoietic stem cells from umbilical cord blood on membranes.  J. Membr. Sci. 351:104-111, 2010
  37. Iinuma, N., T. Sakurai, A. Kamiyoshi, Y. Ichikwawa-Shindo, T. Arai, T. Yoshizawa, T. Koyama, R. Uetake, H. Kawate, S. Muto, Y. Tagawa, S. Miyagawa, T. Shindo: Adrenomedullin in sinusoidal endothelial cells play protective roles against cold injury of liver.  Peptides  31:865-871, 2010
    38. ～2009年
  38. Hu, T., M. Takamoto, S. Hida, Y. Tagawa, K. Sugane: IFN- deficiency worsen Pneumocystis pneumonia with Th17 development in nude mice.  Immunol Lett., 127:55-59, 2009
  39. Motoyama, H., S. Ogawa, A. Kubo, S. Miwa, J. Nakayama, Y. Tagawa, and S. Miyagawa: In vitro reprogramming of adult hepatocytes into insulin-producing cells without viral vectors. Biochem. Biophys. Res. Commun. 385:123-128, 2009
  40. Maruyama, H., M. Takahashi, M. Takamoto, Y. Shiba, H. Ise, J. Koyama, Y. Tagawa, Y. Iwakura, and U. Ikeda: Deficiency of Tumor Necrosis Factor-a and Interferon-g in bone marrow cells synergistically inhibits neointimal formation following vascular injury.  Cardiovasc Res., 80:175-180, 2008
  41. Isoda, K., N. Kagaya, S. Akamatsu, S. Hayashi, M. Tamesada, A. Watanabe, M. Kobayashi, Y. Tagawa, M. Kondoh, M. Kawase, and K. Yagi: Hepatoprotective effect of vitamin b(12) on dimethylnitrosamine-induced liver injury.  Biol. Pharm. Bull. 31:309-311, 2008
  42. Hoshiba, T., H. Nagahara, C. S. Cho, Y. Tagawa, and T. Akaike: Primary hepatocyte survival on non-integrin-recognizable matrices without the activation of Akt signaling.  Biomaterials  28:1093-1104, 2007
  43. Tsutsui, M., S. Ogawa, Y. Inada, E. Tomioka, A. Kamiyoshi, S. Tanaka, T. Kishida, M. Nishiyama, M. Murakami, J. Kuroda, Y. Hashikura, S. Miyagawa, F. Satoh, N. Shibata, and *Y. Tagawa: Characterization of cytochrome P450 expression in murine embryonic stem cell-derived hepatic tissue system.  Drug Metab. Dispos.  34:696-701, 2006
  44. Sato, H., M. Takahashi, H. Ise, A. Yamada, S. Hirose, Y. Tagawa, H. Morimoto, A. Izawa, U. Ikeda: Collagen synthesis is required for ascorbic acid-enhanced differentiation of mouse embryonic stem cells into cardiomyocytes.  Biochem. Biophys. Res. Commun.  342:107-112, 2006
  45. Qian, X, K. Agematsu, G. J. Freeman, Y. Tagawa, K. Sugane, T. Hayashi: ICOS-ligand B7-H2, expressed on Human type II alveolar epithelial cells, plays a role in pulmonary host defense system.  Eur. J. Immunol. 36:906-918, 2006
  46. Kamiyoshi, A., T. Sakurai, Y. Ichikawa-Shindo, J. Fukuchi, H. Kawate, S. Muto, Y. Tagawa, and T. Shindo: Endogenous aCGRP protects against concanavalin A-induced hepatitis in mice.  Biochem. Biophys. Res. Commun.   342:152-158, 2006
  47. Sasaki, S, Y. Tagawa, Y. Iwakura, and A. Nakane: The role of gamma interferon in acquired host resistance against Staphylococcus aureus infection in mice.  FEMS Immunol. Med. Microbiol. 46:367-374, 2006
  48. Tsuchimoto, Y., Y. Yoshida, M. Takeuchi, A. Mine, H. Yatani, Y. Tagawa, B. Meerbeek, K. Suzuki, and T. Kuboki: Effect of surface pre-treatment on durability of resin-based cements bonded to titanium.  Dent. Mater. 22:545-552, 2005
  49. Ogawa, S., *Y. Tagawa, A. Kamiyoshi, A. Suzuki, J. Nakayama, Y. Hashikura, and S. Miyagawa: Crucial roles of mesodermal cell lineages in a murine embryonic stem cell-derived in vitro liver organogenesis system.  Stem Cells  23:903-913,2005
  50. Mita, A., Y. Hashikura, Y. Tagawa, J. Nakayama, M. Kawakubo, and S. Miyagawa: Expression of fas ligand by hepatic macrophages in patients with fulminant hepatic failure.  Am. J. Gastroenterol. 100:2551-2559, 2005
  51. Wakabayashi, T., D.L. Hu, Y. Tagawa, K. Sekikawa, Y. Iwakura, K. Hanada, and A. Nakane: IFN- and TNF-are involved in urushiol-induced contact hypersensitivity in mice.  Immunol. Cell Biol.  83:18-24, 2005
  52. Kagaya, N., A. Kamiyoshi, Y. Tagawa, H. Nagashima, M. Kawase, and K. Yagi.: Tea catechin inhibits rubratoxin B-induced apoptosis of hepatocyte through MAPK p38 pathway.  Micotoxins 55, 17-22, 2005
  53. Kagaya, N., A. Kamiyoshi, Y. Tagawa, H. Nagashima, M. Kawase, and K. Yagi.: Interaction of rubratoxin B with serum albumin.  Micotxins 55, 23-26, 2005.
  54. Kagaya, N., A. Kamiyoshi, Y. Tagawa, S. Akamatsu, K. Isoda, M. Kawase, and K. Yagi: Suppression of cell death in primary rat hepatocytes by alpha1-acid glycoprotein. J. Biosci. Bioeng.　99:81-83, 2005
  55. Hasegawa, S., Nishikawa, S., Miura, T., Saito, Y., Madarame, H., Sekikawa, K., Tagawa, Y., Iwakura, Y., and Nakane, A.: Tumor necrosis-alpha is required for gastritis induced by Helicobacter felis infection in mice.  Microb. Pathog.  37:119-124, 2004
  56. Yoshida, Y., K. Nagakane, R. Fukuda, Y. Nakayama, M. Okazaki, H. Shintani, S. Inoue, Y. Tagawa, K. Suzuki, J. De Munck, and B. Van Meerbeek : Comparative Study on Adhesive Performance of Functional Monomers.  J. Dental Research, 83:454-458, 2004   
  57. Kawase, M., N. Kagaya, S. Akamatsu, A. Kamiyoshi, S. Muto, Y. Tagawa, and Y. Yagi.: Liver protection by bis(maltolato)zinc(II) complex.  Exp. Anim.  53:1-9, 2004
  58. Sakuraba H, Ishiguro Y, Yamagata K, Tagawa Y, Iwakura Y, Sekikawa K, Munakata A, Nakane A.: Transforming growth factor- regulates susceptibility of epithelial apoptosis in murine model of colitis. Ann. N.Y. Acad. Sci.1029:382-384, 2004
  59. Kagaya, N., Y. Hara, R. Saijo, A. Kamiyoshi, Y. Tagawa, M. Kawase, and K. Yagi.: Novel function of rare catechin, epigallocatechin-3-(3’’-O-methyl)gallate, against cold injury in primary rat hepatocytes.  J. Biosci. Bioeng. 96:559-563, 2003
  60. Sehra, S., Pynaert, G.., Tournoy, K., Haegenman, A., Matthys, P., Tagawa, Y., Pauwels, R., Grooten, J.: Airway IgG counteracts specific and bystander allergen-triggered pulmonary inflammation by a mechanism dependent on FcgR and IFN-g. J. Immunol., 171:2080-2089, 2003
  61. Johkura, K., Cui, L., Suzuki, A., Teng, R., Kamiyoshi, A., Okamura, S., Kubota, S., Zhao, X.,  Asanuma, K., Okouchi, Y., Ogiwara, N., Tagawa,　Y., and Sasaki, K.: Survival and function of mouse embryonic stem cell-derived cardiomyocytes in ectopic transplants. Cardiovascular Research 　58:435-443, 2003
  62. Kyuwa, S., Kawamura, S., Tagawa, Y., Iwakura, Y., Urano, T., and Yoshikawa, Y.: Differences between BALB/c and C57BL/6 in mouse hepatitis virus replication in primary hepatocyte culture.  Exp. Anim., 52:81-84, 2003
  63. Nakae, S., Komiyama, Y., Narumi, S., Sudo, K., Horai, R., Tagawa, Y., Sekikawa, K., Matsushima, K., Asano, M., Iwakura, Y.: IL-1-induced tumor necrosis factor- elicits inflammatory cell infiltration in the skin by inducing IFN-g-inducible protein 10 in the elicitation phase of the contact hypersensitivity response. Int. Immunol. , 15: 251-260, 2003
  64. Kagaya, N., Tagawa, Y., Nagashima, H., Saijo, R., Kawase, M., Yagi, K. : Suppression of cytotoxin-induced cell death in isolated hepatocytes by tea catechins.  Eur. J. Pharmacol.  450: 231-236, 2002
  65. Kakuta, S., Tagawa, Y., Shibata, S., Nannno, M., and Iwakura, Y.: Inhibition of B16 melanoma metastasis by interferon- through direct inhibition of cell proliferation and activation of anti-tumor host mechanisms.  Immunology.  105 : 92-100, 2002
  66. Mizuki, M., Nakane, A., Sekikawa, K., Tagawa, Y., Iwakura, Y., : Comparison of host resistance to primary and secondary Listeria monocytogenes infections in mice by intranasal and intravenous routes.  Infect. Immun. 70:4805-4811, 2002
  67. Sasaki, S., Omoe, K., Tagawa, Y., Iwakura, Y., Sekikawa, K., Shinagawa, K., Nakane, A. : Roles of gamma interferon and tumor necrosis factor-alpha in shiga toxin lethality.  Microbial Pathogenesis.  33: 43-47, 2002
  68. Kyuwa, S., Shibata, S., Tagawa, Y., Iwakura, Y., Machii, K., Urano, T.: Acute hepatic failure in IFN-g-deficient BALB/c mice after murine coronavirus infection. Virus Res. 83: 169-177, 2002
  69. Kagaya, N., Kawase, M., Maeda, H., Tagawa, Y., Nagashima, H., Ohmori, H., and Yagi, K.: Enhancing effect of zinc on hepatoprotectivity of epigallocatechin gallate in isolated rat hepatocytes.  Biol. Pharm. Bull.  25: 1156-1160, 2002
  70. Miura, T., Kudo, T., Matsuki, A., Sekikawa, K., Tagawa, Y., Iwakura, Y., Nakane, A.　Effect of 6-hydroxydopamine on host resistance against Listeria monocytogenes infection. Infect. Immun.  69:7234-7241, 2001
  71. Norose, K., Mun, H. S., Aosai, F., Chen, M., Hata, H., Tagawa, Y., Iwakura, Y., and Yano, A. : Organ infectivity of Toxoplasma gondii in interferon-gamma knockout mice. J. Parasitol. 87:447-452, 2001
  72. Yoneto, T., Waki, S., Takai, T., Tagawa, Y., Iwakura, Y., Mizuguchi, J., Nariuchi, H., and Yoshimoto, T.  :  A critical role of Fc receptor-mediated antibody-dependent phagocytosis in the host resistance to blood-stage plasmodium berghei  XAT Infection. J. Immunol.   166: 6236-6241, 2001
  73. Tagawa, Y., P. Matthys, H. Heremans, C. Dillen, Z. Zaman, Y. Iwakura, and A. Billiau. : Bimodal role of endogenous interleukin-6 in concanavalin A-induced hepatitis in mice. J. Leukoc. Biol. 67:90-96, 2000
  74. Tanaka, J., H. Ozaki, J. Yasuda, R. Horai, Y. Tagawa, M. Asano, S. Saijo, M. Imai, K. Sekikawa, M. Kopf, and Y. Iwakura. : Lipopolysaccharide-induced HIV-1 expression in transgenic mice is mediated by tumor necrosis factor-α and interleukin-1, but not by interferon-g nor interleukin-6. AIDS 14:1299-1307, 2000
  75. Sasaki, S., S. Nishikawa, T. Miura, M. Mizuki, K. Yamada, H. Madarame, Y. Tagawa, Y. Iwakura, and A. Nakane. : Interleukin-4 and interleukin-10 are involved in host resistance to Staphylococcus aureus infection through regulation of gamma interferon. Infect. Immun. 68:2424-2430, 2000
  76. Miura, T., S. Nishikawa, S. Sasaki, K. Yamada, S. Hasegawa, D. Mizuki, M. Mizuki, I. Hatayama, K. Sekikawa, Y. Tagawa, Y. Iwakura, and A. Nakane. : Roles of endogenous cytokines in liver apoptosis of mice in lethal Listeria monocytogenes infection. FEMS Immunol. Med. Microbiol. 28:335-341, 2000
  77. Mun H. S., F. Aosai, K. Norose, M. Chen, H. Hata, Y. Tagawa, Y. Iwakura, D. Byun, and A. Yano. : Toxoplasma gondi Hsp 70 as a danger signal in Toxoplasma gondi-infected mice.  Cell stress Chaperones.  5: 328-335, 2000
  78. Hino, A., O. Igarashi, Y. Tagawa, Y. Iwakura, and H. Nariuchi. : Interferon-g priming is not critical for IL-12 production of murine spleen cells. Cytokine. 12:12-20, 2000
  79. Matsumoto, K., N. Matsushita, H. Tomozawa, and Y. Tagawa. : Hematological characteristics of rats spontaneously developing eosinophilia. Exp. Anim. 49:211-215, 2000　
  80. Kotani, M., Y. Tagawa, and Y. Iwakura. : Involvement of autoimmunity against type II collagen in the development of arthritis in mice transgenic for the human T cell leukemia virus type I tax gene.  Eur. J. Immunol. 29:54-64, 1999
  81. Shimada, S., M. Kawaguchi-Miyashita, A. Kushiro, T. Sato, M. Nanno, T. Sako, Y. Matsuoka, K. Sudo, Y. Tagawa, Y. Iwakura, and M. Ohwaki. 1999. Generation of polymeric immunoglobulin receptor-deficient mouse with marked reduction of secretory IgA.  J. Immunol. 163:5367-5373, 1999
  82. Hyodo, Y., K. Matsui, N. Hayashi, H. Tsutsui, S. Kashiwamura, H. Yamauchi, K. Hiroishi, K. Takeda, Y. Tagawa, Y. Iwakura, N. Kayagaki, M. Kurimoto, H. Okamura, T. Hada, H. Yagita, S. Akira, K. Nakanishi, and K. Higashino. :  IL-18 up-regulates perforin-mediated NK activity without increasing perforin messenger RNA expression by binding to constitutively expressed IL-18 receptor. 　　J. Immunol. 162:1662-1668, 1999
  83. Igarashi, I., R. Suzuki, S. Waki, Y. Tagawa, S. Seng, S. Tum, Y. Omata, A. Saito, H. Nagasawa, Y. Iwakura, N. Suzuki, T. Mikami, and Y. Toyoda.: Roles of CD4(+) T cells and gamma interferon in protective immunity against Babesia microti infection in mice. Infect. Immun. 67:4143-48, 1999
  84. Tsuji, H., N. Mukaida, A. Harada, S. Kaneko, E. Matsushita, Y. Nakanuma, H. Tsutsui, H. Okamura, K. Nakanishi, Y. Tagawa, Y. Iwakura, K. Kobayashi, and K. Matsushima. : Alleviation of lipopolysaccharide-induced acute liver injury in Propionibacterium acnes-primed IFN-g-deficient mice by a concomitant reduction of TNF-a, IL-12, and IL-18 production. J. Immunol. 162:1049-1055, 1999
  85. Sawai, N., M. Kita, T. Kodama, T. Tanahashi, Y. Yamaoka, Y. Tagawa, Y. Iwakura, and J. Imanishi. : Role of gamma interferon in Helicobacter pylori-induced gastric inflammatory responses in a mouse model. Infect. Immun. 67:279-285, 1999
  86. He, J., H. Ichimura, T. Iida, M. Minami, K. Kobayashi, M. Kita, C. Sotozono, Y. Tagawa, Y. Iwakura, and J. Imanishi. : Kinetics of cytokine production in the cornea and trigeminal ganglion of C57BL/6 mice after corneal HSV-1 infection.           J. Interferon Cytokine Res. 19:609-615, 1999
  87. Kobayashi, M., F. Aosai, H. Hata, H. S. Mun, Y. Tagawa, Y. Iwakura, and A. Yano. : Toxoplasma gondii: difference of invasion into tissue of digestive organs between susceptible and resistant strain and influence of IFN-gamma in mice inoculated with the cysts perorally. J. Parasitol. 85:973-975, 1999
  88. Tagawa, Y., S. Kakuta, and Y. Iwakura. : Involvement of Fas/Fas ligand system-mediated apoptosis in the development of concanavalin A-induced hepatitis. Eur. J. Immunol. 28:4105-4113, 1998
  89. Kyuwa, S., Y. Tagawa, S. Shibata, K. Doi, K. Machii, and Y. Iwakura. 1998. Murine coronavirus-induced subacute fatal peritonitis in C57BL/6 mice deficient in gamma interferon. J. Virol. 72:9286-9290, 1998
  90. Flamand, V., V. Donckier, F. X. Demoor, A. Le Moine, P. Matthys, M. L. Vanderhaeghen, Y. Tagawa, Y. Iwakura, A. Billiau, D. Abramowicz, and M. Goldman. :  CD40 ligation prevents neonatal induction of transplantation tolerance.  J. Immunol. 160:4666-4669, 1998
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